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30 year old male. had gout for 1 year. 1st attack so bad that it developed tophi in my big toe joint. Uric acid was 9.6 at the time. Made some diet changes but that only brought me down to 7.4. I have gout attacks quite often, but most are mild. Ive been on 100mg allopurinol for a month with no side effects. Uric acid is now 6.2 so I had my dosage increased to 200mg so I can get below 6. It is very important to get on daily colchicine (0.6mg twice a day) while starting allopurinol. I learned the hard way.



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Although some medications such as NSAIDs can be taken to reduce uric acid levels, you should not start or stop taking preventative gout medications like Allopurinol and Probenecid during a gout flare-up.

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Here, and with all other recommendations for drug therapy in Parts I and II of the 2012 ACR Guidelines for gout, the recommendations assumed a lack of contra-indications, intolerance, serious adverse events, or drug-drug interactions for given agents.

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